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Article

Correlation of drug resistance with Single Nucleotide Variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of <i>M.tuberculosis</i>

2020-03-08

Abstract excerpt

<h4>Background</h4> Genome sequencing and genetic polymorphism analysis of clinical isolates of M.tuberculosis is carried out to gain further insight into molecular pathogenesis and host-pathogen interaction. Therefore the functional evaluation of the effect of single nucleotide variation (SNV) is essential. At the same time, the identification of invariant sequences unique to M.tuberculosis contributes to infe...

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Literature Corpus work
1abe25ac-ac92-534f-989b-2bbfc6a4e8a7
DOI
10.1101/2020.03.07.981878
Open publication

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Correlation of drug resistance with Single Nucleotide Variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of <i>M.tuberculosis</i>DOI 10.1101/2020.03.07.981878
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