Article
Single nucleotide polymorphism in the genes of mce1 and mce4 operons of Mycobacterium tuberculosis: analysis of clinical isolates and standard reference strains.
BMC microbiology - 23 Feb 2011
Pasricha Rashmi, Chandolia Amita, Ponnan Prija, Saini Neeraj Kumar, Sharma Sangeeta, Chopra Madhu, Basil Mandira Varma, Brahmachari Vani, Bose Mridula
Abstract excerpt
BACKGROUND: The presence of four mammalian cell entry (mce) operons in Mycobacterium tuberculosis suggests the essentiality of the functions of the genes in these operons. The differential expression of the four mce operons in different phases of in vitro growth and in infected animals reported earlier from our laboratory further justifies the apparent redundancy for these genes in the genome.Here we investigate...
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