Article

Insertion and deletion evolution reflects antibiotics selection pressure in a <i>Mycobacterium tuberculosis</i> outbreak

2020-01-28

Abstract excerpt

In genome evolution, genetic variants are the source of diversity, which natural selection acts upon. Treatment of human tuberculosis (TB) induces a strong selection pressure for the emergence of antibiotic resistance in the infecting Mycobacterium tuberculosis (MTB) strains. MTB evolution in response to treatment has been intensively studied and mainly attributed to point substitutions. However, the contribution...

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Literature Corpus work: 06602adb-6c9a-5e1a-b794-92039d40207c
DOI: 10.1101/2020.01.28.922765

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