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Copy number variation analysis of 9,482 <i>Mycobacterium tuberculosis</i> isolates identifies lineage-specific molecular determinants

2024-10-17

Abstract excerpt

<h4>Background</h4> Clinical manifestations of tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) show lineage-specific differences contributed by genetic polymorphism such as phylo-single nucleotide variations (PhyloSNPs) and insertion or deletions (INDELs). Intragenomic rearrangement events, such as gene duplications and deletions, may cause gene copy number differences in Mtb, contributing to lineag...

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Literature Corpus work
d8bbceb0-4c5a-5196-8d19-618ee8295c0b
DOI
10.1101/2024.10.15.618387
Open publication

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Copy number variation analysis of 9,482 <i>Mycobacterium tuberculosis</i> isolates identifies lineage-specific molecular determinantsDOI 10.1101/2024.10.15.618387
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