Article

Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response

2024-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Plant homeodomain (PHD) fingers are critical effectors of histone post-translational modifications (PTMs), acting as regulators of gene expression and genome integrity, and frequently presenting in human disease. While most PHD fingers recognize unmodified and methylated states of histone H3 lysine 4 (H3K4), the specific functions of many of the over 100 PHD finger-containing proteins in humans...

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Literature Corpus work: 1a7bd233-c3e4-553e-8690-761481c0310a
DOI: 10.1101/2024.11.20.623956

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