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The Ancient Origin and Dynamic Diversification of the Fungal Poly(ADP)-ribose Polymerase Protein Family

2026-07-26

Abstract excerpt

<h4>ABSTRACT</h4> Poly(ADP-ribose) polymerases (PARPs) catalyze ADP-ribosylation, a conserved post- translational modification involved in DNA repair, transcriptional regulation, and chromatin remodeling. Although extensively studied in animals, the evolution and diversification of PARPs across the fungal kingdom remain largely unexplored. Here, we present the first kingdom-wide comparative genomic analysis of PA...

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Literature Corpus work
a6114692-46a0-5268-8b9a-418b48e444ce
DOI
10.64898/2026.07.25.740670
Open publication

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