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Zinc finger proteins: guardians of genome stability

25 Jul 2024

Abstract excerpt

Zinc finger proteins (ZNF), a unique yet diverse group of proteins, play pivotal roles in fundamental cellular mechanisms including transcription regulation, chromatin remodeling, protein/RNA homeostasis, and DNA repair. Consequently, the mis regulation of ZNF proteins can result in a variety of human diseases, ranging from neurodevelopmental disorders to several cancers. Considering the promising results of DNA...

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DNA Repair Mechanisms
Genomics and Chromatin Dynamics
PARP inhibition in cancer therapy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39119040
DOI: 10.3389/fcell.2024.1448789

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