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Article

PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks.

Mutation research - 1 Dec 2008

Baker Lindsey A, Allis C David, Wang Gang G

Abstract excerpt

Histone covalent modifications regulate many, if not all, DNA-templated processes, including gene expression and DNA damage response. The biological consequences of histone modifications are mediated partially by evolutionarily conserved "reader/effector" modules that bind to histone marks in a modification- and context-specific fashion and subsequently enact chromatin changes or recruit other proteins to do so....

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Source

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Identifiers

PMID: 18682256
DOI: 10.1016/j.mrfmmm.2008.07.004
PMCID: PMC2656448

Genes

ATRX
NSD1
RAG2
SET

Provenance

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