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Article

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.

Cell reports - 18 Oct 2016

Klein Brianna J, Wang Xiaoyan, Cui Gaofeng, Yuan Chao, Botuyan Maria Victoria, Lin Kevin, Lu Yue, Wang Xiaolu, Zhao Yue, Bruns Christiane J, Mer Georges, Shi Xiaobing, Kutateladze Tatiana G

Abstract excerpt

PHF20 is a core component of the lysine acetyltransferase complex MOF (male absent on the first)-NSL (non-specific lethal) that generates the major epigenetic mark H4K16ac and is necessary for transcriptional regulation and DNA repair. The role of PHF20 in the complex remains elusive. Here, we report on functional coupling between methylation readers in PHF20. We show that the plant homeodomain (PHD) finger of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27760318
DOI: 10.1016/j.celrep.2016.09.056
PMCID: PMC5125728

Genes

PHF20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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