Article

The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern

2018-10-22

Abstract excerpt

Genetic interactions, a phenomenon whereby combinations of mutations lead to unexpected effects, reflect how cellular processes are wired and play an important role in complex genetic diseases. Understanding the molecular basis of genetic interactions is crucial for deciphering pathway organization as well as understanding the relationship between genetic variation and disease. Several putative molecular mechanism...

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Literature Corpus work: 1a671e18-11d4-576d-b66e-0abe0b813b75
DOI: 10.1101/449520

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