Article

Molecular architecture of the human caveolin-1 complex

2022-02-17

Abstract excerpt

Membrane sculpting proteins shape the morphology of cell membranes and facilitate remodeling in response to physiological and environmental cues. Complexes of the monotopic membrane protein caveolin function as essential curvature-generating components of caveolae, flask-shaped invaginations that sense and respond to plasma membrane tension. However, the structural basis for caveolin’s membrane remodeling activity...

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Literature Corpus work: 191dd956-666c-5e4d-9eee-4c90a4e90394
DOI: 10.1101/2022.02.17.480763

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