Article
The Biology of Caveolae: Lessons from Caveolin Knockout Mice and Implications for Human Disease
1 Dec 2003
Abstract excerpt
Caveolae, plasma membrane invaginations that serve as membrane organizing centers, are found in most cell types, but are enriched in adipocytes, endothelial cells, and myocytes. Three members of the caveolin family (Cav-1, -2, and -3) are essential for the formation of caveolae. Specialized motifs in the caveolin proteins function to recruit lipids and proteins to caveolae for participation in intracellular...
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