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Clinicopathological features of pathogenic, non-pathogenic, and unknown significance (NP/US) POLE mutations in endometrial carcinomas: A study based on actual world

2025-07-02

Abstract excerpt

<title>Abstract</title> <p> While 11 pathogenic mutations of the DNA polymerase epsilon ( <italic>POLE</italic> ) gene are recognized, the pathogenicity of additional mutations and their association with clinicopathological features remain unclear. This study investigates the clinicopathological features of endometrial carcinomas (ECs) with pathogenic, non-pathogenic, and unknown significance (NP/US) <italic>...

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Literature Corpus work
19103bb0-88ac-5e83-9dd3-938156a031c9
DOI
10.21203/rs.3.rs-6689956/v1
Open publication

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Clinicopathological features of pathogenic, non-pathogenic, and unknown significance (NP/US) POLE mutations in endometrial carcinomas: A study based on actual worldDOI 10.21203/rs.3.rs-6689956/v1
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