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Article

Gold nanocarriers for transport of oligonucleotides across brain endothelial cells

2020-07-13

Abstract excerpt

Treatment of diseases that affect the CNS by gene therapy requires delivery of oligonucleotides to target cells within the brain. As the blood brain barrier prevents movement of large biomolecules, current approaches involve direct injection of the oligonucleotides, which is invasive and may have only a localised effect. The aim of this study was to investigate the potential of 2 nm galactose-coated gold nanoparti...

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Identifiers and source

Literature Corpus work
18f945a9-cedd-5814-9837-4abb9a423c37
DOI
10.1101/2020.07.13.200352
Open publication

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Gold nanocarriers for transport of oligonucleotides across brain endothelial cellsDOI 10.1101/2020.07.13.200352
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