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Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays

2021-02-09

Abstract excerpt

<h4>Background</h4> The pathways that control protein transport across the Blood-Brain Barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro , current models are not suitable for systematic analysis of the molecular mechanisms of antibody transport. The gaps in our mechanistic understanding of antibody transcytosis hinder new therapeutic delivery strategy deve...

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Literature Corpus work
05032d27-fc4a-5599-9eba-c5797f750a8b
DOI
10.1101/2021.02.09.430382
Open publication

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Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arraysDOI 10.1101/2021.02.09.430382
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