Article
Crocetin delays brain and body aging by increasing cellular energy levels and enhances the median life span in aged C57BL/6J mice
2023-10-04
Abstract excerpt
Abstract Background and Purpose Aging is usually accompanied by mitochondrial dysfunction, reduced energy levels, and cell death in the brain and other tissues. Mitochondria play a crucial role in maintaining cellular energy through oxidative phosphorylation (OXPHOS). However, OXPHOS is impaired as mitochondrial oxygen supply decreases with age. We explored whether pharmacologically increased oxygen diffusion by c...
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Identifiers and source
- Literature Corpus work
- 18e74eb9-f935-5170-9aff-693a1a9a8ad7
- DOI
- 10.22541/au.169639653.39291350/v1
