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Tissue-Specific Landscape of Metabolic Dysregulation during Ageing

7 Feb 2021

Abstract excerpt

The dysregulation of cellular metabolism is a hallmark of ageing. To understand the metabolic changes that occur as a consequence of the ageing process and to find biomarkers for age-related diseases, we conducted metabolomic analyses of the brain, heart, kidney, liver, lung and spleen in young (9-10 weeks) and old (96-104 weeks) wild-type mice [mixed genetic background of 129/J and C57BL/6] using NMR...

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PMID: 33562384
DOI: 10.3390/biom11020235

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