Article

CNAHap: a germline haplotyping method using tumor allele-specific copy number alteration

2021-03-29

Abstract excerpt

Haplotype phasing is indispensable to study human genetics. The pervasiveness of large copy number variant segments in solid tumors brings possibilities to resolve long germline phasing blocks utilizing allele imbalance in tumor data. Although there exist such studies, none of them provide easy-use software based on availability and usability. Herein, we present a novel tool, CNAHap, to determine the allele-specif...

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Literature Corpus work: 18adc99c-5684-58e4-b4d9-832e834c3e68
DOI: 10.1101/2021.03.27.437314

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