Article

Human peripheral monocytes capture elements of the state of microglial activation in the brain

2022-01-14

Abstract excerpt

<title>Abstract</title> <p>Despite a growing focus on neuroimmune mechanisms of Alzheimer’s disease (AD), the role of peripheral monocytes remains largely unknown. Circulating monocytes communicate with the brain’s resident myeloid cells, microglia, via chemical signaling and can directly infiltrate the brain parenchyma.<sup>1</sup> Thus, molecular signatures of monocytes may serve as indicators of neuropathologi...

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Literature Corpus work: 18a28eb3-7e9c-5bd9-b629-3b5a71941ff6
DOI: 10.21203/rs.3.rs-1226021/v1

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