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Decoding monocyte signatures in ischemic stroke: A multi-scale transcriptomic approach

3 Sept 2025

Abstract excerpt

Monocytes play a crucial role in post-stroke immune infiltration, yet the intricate immune regulatory networks they orchestrate in ischemic stroke remain poorly understood. This knowledge gap has hindered the development of targeted monocyte-based therapies for stroke. Here, we used a multi-omics approach combining single-cell and bulk transcriptomics. CellChat analysis revealed intercellular communication...

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PMID: 40903972
DOI: 10.4103/nrr.nrr-d-24-01669

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