Article

Nicotinamide Riboside Enhances Mitochondrial Bioenergetics and Dopaminergic Signaling Independent of Neuron Survival in a Double-Hit Parkinson’s Model

2026-06-19

Abstract excerpt

<title>Abstract</title> <p> Background: Parkinson’s disease (PD) is characterized by progressive degeneration of <italic>substantia nigra pars compacta</italic> (SNc) dopaminergic (DA) neurons and the development of motor and non-motor impairments. Mitochondrial dysfunction, exacerbated by aging and environmental exposures, is a central contributor to PD pathogenesis. Nicotinamide riboside (NR), a dietary pre...

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Literature Corpus work: 181ff87e-f304-5558-8c12-1acbbd2f4e4c
DOI: 10.21203/rs.3.rs-9970859/v1

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Nicotinamide Riboside Enhances Mitochondrial Bioenergetics and Dopaminergic Signaling Independent of Neuron Survival in a Double-Hit Parkinson’s ModelDOI 10.21203/rs.3.rs-9970859/v1Read

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