Article
-NMDA R/+VDR pharmacological phenotype as a novel therapeutic target in relieving motor-cognitive impairments in Parkinsonism.
Drug and chemical toxicology - 1 Oct 2015
Ogundele Olalekan Michael, Nanakumo Ednar Tarebi, Ishola Azeez Olakunle, Obende Oluwafemi Michael, Enye Linus Anderson, Balogun Wasiu Gbolahan, Cobham Ansa Emmanuel, Abdulbasit Amin
Abstract excerpt
BACKGROUND: Parkinsonism describes Parkinson's disease and other associated degenerative changes in the brain resulting in movement disorders. The motor cortex, extrapyramidal tracts and nigrostriatal tract are brain regions forming part of the motor neural system and are primary targets for drug or chemotoxins induced Parkinsonism. The cause of Parkinsonism has been described as wide and elusive, however,...
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