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Article

Nicotine-mediated therapy for Parkinson’s disease in transgenic Caenorhabditis elegans model

15 May 2024

Abstract excerpt

Parkinson’s disease resultant in the degeneration of Dopaminergic neurons and accumulation of α-synuclein in the substantia nigra pars compacta. The synthetic therapeutics for Parkinson’s disease have moderate symptomatic benefits but cannot prevent or delay disease progression. In this study, nicotine was employed by using transgenic Caenorhabditis elegans Parkinson’s disease models to minimize the Parkinson’s...

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PMID: 38813528
DOI: 10.3389/fnagi.2024.1358141

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