Article

Quantitative profiling of DNA 6mA at single-base resolution using NAME-seq

2022-11-23

Abstract excerpt

<title>Abstract</title> <p>DNA N6-methyladenine (6mA) is prokaryotes' most prevalent type of DNA methylation. Recently, 6mA has been identified in eukaryotic genomes, but the prevalence of 6mA in eukaryotes has been debated due to the limitations of current 6mA genomic profiling and quantification methods. To solve the challenges, we develop a chemical-based sequencing method, Nitrite-assisted Amino MEthylation s...

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Literature Corpus work: 17b52166-c4b9-577f-a140-afb993074a69
DOI: 10.21203/rs.3.rs-2286301/v1

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