Article

Direct RNA sequencing enables improved transcriptome assessment and tracking of RNA modifications for medical applications

2025-03-24

Abstract excerpt

<title>Abstract</title> <p>Direct RNA sequencing (DRS) is a nanopore-based technique for analyzing RNA in its native form, promising breakthroughs in diagnostics and biomarker development. Coupled to RNA002 sequencing chemistry, its clinical implementation has been challenging due to low throughput, low accuracy, and lack of large-scale RNA-modification models. In this study, we evaluate the improvements achieved...

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Literature Corpus work: 75bf5ddc-716d-5be4-9625-4f405343e642
DOI: 10.21203/rs.3.rs-5567289/v1

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