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Article

Selective Effect of DNA N6-Methyladenosine Modification on Transcriptional Genetic Variations in East Asian Samples.

International journal of molecular sciences - 27 Sept 2024

Luan Meiwei, Chen Kaining, Zhao Wenwen, Tang Minqiang, Wang Lingxia, Liu Shoubai, Zhu Linan, Xie Shangqian

Abstract excerpt

Genetic variations and DNA modification are two common dominant factors ubiquitous across the entire human genome and induce human disease, especially through static genetic variations in DNA or RNA that cause human genetic diseases. DNA N6-methyladenosine (6mA) methylation, as a new epigenetic modification mark, has been widely studied for regulatory biological processes in humans. However, the effect of DNA...

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PMID: 39408729
DOI: 10.3390/ijms251910400
PMCID: PMC11477068

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