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N <sup>6</sup> -Methyladenine DNA Modification in Human Genome

2017-08-16

Abstract excerpt

<h4>Summary</h4> DNA N6-methyladenine (6mA) modification is the most prevalent DNA modification in prokaryotes, but whether it exists in human cells and whether it plays a role in human diseases remain enigmatic. Here, we showed that 6mA is extensively present in human genome, and we cataloged 881,240 6mA sites accounting for ∼0.051% of the total adenines. [G/C]AGG[C/T] was the most significantly associated motif...

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Literature Corpus work
63dcee1c-8285-50e3-ad40-42454437c2d9
DOI
10.1101/176958
Open publication

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N <sup>6</sup> -Methyladenine DNA Modification in Human GenomeDOI 10.1101/176958
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