Article

Methyl-SNP-seq reveals dual readouts of methylome and variome at molecule resolution

2022-07-02

Abstract excerpt

Covalent modifications of genomic DNA are crucial for most organisms to survive. Amplicon-based high throughput sequencing technologies erase all DNA modifications to retain only sequence information for the four canonical nucleobases, necessitating specialized technologies for ascertaining epigenetic information. To also capture base modification information, we developed Methyl-SNP-seq, a technology that takes a...

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Literature Corpus work: 663a8236-0ed1-59bd-a4e2-672427280fc0
DOI: 10.1101/2022.06.28.498010

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