Article
MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing.
Nucleic acids research - 4 Jan 2017
Ye Pohao, Luan Yizhao, Chen Kaining, Liu Yizhi, Xiao Chuanle, Xie Zhi
Abstract excerpt
DNA methylation is an important type of epigenetic modifications, where 5- methylcytosine (5mC), 6-methyadenine (6mA) and 4-methylcytosine (4mC) are the most common types. Previous efforts have been largely focused on 5mC, providing invaluable insights into epigenetic regulation through DNA methylation. Recently developed single-molecule real-time (SMRT) sequencing technology provides a unique opportunity to...
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