Article

EIF3H Sustains Translational Programs Essential for Proliferation in Human Primed Pluripotency

2026-05-20

Abstract excerpt

<h4>ABSTRACT</h4> Pluripotent stem cells (PSCs) have remarkable capacity for unlimited self-renewal and differentiation into all somatic lineages. Although translational regulation has been implicated in the maintenance of PSC identity, the specific mechanisms involved remain poorly understood. Here, we identified EIF3H, a conserved subunit of the eIF3 translation initiation complex, as an essential regulator of...

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Literature Corpus work: 179e49ec-8bb7-535f-b44c-47b183fbca93
DOI: 10.64898/2026.05.18.725809

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