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Article

The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation.

Stem cell reports - 8 Dec 2020

Lezmi Elyad, Weissbein Uri, Golan-Lev Tamar, Nissim-Rafinia Malka, Meshorer Eran, Benvenisty Nissim

Abstract excerpt

Chromatin regulators play fundamental roles in controlling pluripotency and differentiation. We examined the effect of mutations in 703 genes from nearly 70 chromatin-modifying complexes on human embryonic stem cell (ESC) growth. While the vast majority of chromatin-associated complexes are essential for ESC growth, the only complexes that conferred growth advantage upon mutation of their members, were the...

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Identifiers

PMID: 32559458
DOI: 10.1016/j.stemcr.2020.05.014
PMCID: PMC7724477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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