Article

eIF3 engages with 3’-UTR termini of highly translated mRNAs

2023-11-11

Abstract excerpt

<h4>ABSTRACT</h4> Stem cell differentiation involves a global increase in protein synthesis to meet the demands of specialized cell types. However, the molecular mechanisms underlying this translational burst and the involvement of initiation factors remains largely unknown. Here, we investigate the role of eukaryotic initiation factor 3 (eIF3) in early differentiation of human pluripotent stem cell (hPSC)-derive...

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Literature Corpus work: 54af8a54-56c3-5ee7-b6c5-369522c023a6
DOI: 10.1101/2023.11.11.566681

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