Article

Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art <i>in vitro</i> and mouse infection models

2020-03-29

Abstract excerpt

<h4>ABSTRACT</h4> Hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) worldwide. The prolyl hydroxylase domain (PHD)-hypoxia inducible factor (HIF) pathway is a key mammalian oxygen sensing pathway and is frequently perturbed by pathological states including infection and inflammation. We discovered a significant upregulation of hypoxia regulated gene transcripts in patients with chroni...

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Literature Corpus work: 176d3a0d-6962-5a76-8548-414714fef3f3
DOI: 10.1101/2020.03.27.011841

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Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art <i>in vitro</i> and mouse infection modelsDOI 10.1101/2020.03.27.011841Read

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