Article

Analysis of Host Factor Networks during Hepatitis B Virus Infection in Primary Human Hepatocytes

2024-05-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Hepatitis B virus (HBV) affects around 250 million people worldwide, causing approximately 887,000 deaths annually, primarily owing to cirrhosis and hepatocellular carcinoma (HCC). The current approved treatments for chronic HBV infection, such as interferon and nucleos(t)ide analogs, have certain limitations as they cannot completely eradicate covalently closed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4083754b-e9eb-5024-9e7c-a0b8294275a9
DOI: 10.21203/rs.3.rs-4321520/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Analysis of Host Factor Networks during Hepatitis B Virus Infection in Primary Human HepatocytesDOI 10.21203/rs.3.rs-4321520/v1Read

Transcriptome-Wide Analysis of Hepatitis B Virus-Mediated Changes to Normal Hepatocyte Gene ExpressionSemantic proximity Read

Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replicationSemantic proximity Read

Bioinformatic Identification and Validation of Key Genes and Biological Pathways Involved in Hepatitis B Virus-related Hepatocellular CarcinomaSemantic proximity Read

Comparative Transcriptomic and Epigenomic Analysis Highlights Hepatitis B Virus Infection Impact on Hepatocellular Carcinoma DevelopmentSemantic proximity Read

Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systemsSemantic proximity Read

A comprehensive comparison of molecular and phenotypic profiles between hepatitis B virus (HBV)-infected and non-HBV-infected hepatocellular carcinoma by multi-omics analysis.Semantic proximity Read

Multiomics Interrogation into HBV (Hepatitis B Virus)-Host Interaction Reveals Novel Coding potential in Human Genome, and Identifies Canonical and Non-canonical Proteins as Host Restriction Factors against HBVSemantic proximity Read

Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBVSemantic proximity Read

PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLFSemantic proximity Read

Molecular Insights into Hepatitis Virus-Induced HepatocarcinogenesisSemantic proximity Read

The HBV web: An insight into molecular interactomes between the hepatitis B virus and its host en route to hepatocellular carcinoma.Semantic proximity Read

Hepatitis B Virus Deregulates the Cell Cycle To Promote Viral Replication and a Premalignant PhenotypeSemantic proximity Read