Article
Association between hypoxia-inducible factor-1α gene polymorphisms and risk of chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: a retrospective case-control study.
Gene - 10 Jun 2015
Lu Yu, Sui Jingzhe, Liu Yanqiong, Li Ruolin, Ma Liping, Zhang Xiaolian, Qin Xue, Li Shan
Abstract excerpt
BACKGROUND: Our recent study demonstrated a significant association between HIF-1α polymorphisms and hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Since chronic hepatitis B (CHB), liver cirrhosis (LC), and HCC are progressive stages of chronic HBV infection, the aim of this study is to further determine if HIF-1α polymorphisms are associated with CHB and HBV-related LC. METHODS: Two HIF-1α...
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