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Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss

2023-03-22

Abstract excerpt

Alzheimer’s disease (AD) is the leading cause of dementia worldwide, but there are limited therapeutic options and no current cure. While the involvement of microglia in AD has been highly appreciated, the role of other innate and adaptive immune cells remains largely unknown, partly due to their scarcity and heterogeneity. This study aimed to study non-microglial immune cells in wild type and AD-transgenic mouse...

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Literature Corpus work
1763149f-a3b8-5d3c-b6ac-5a79bbeb73a5
DOI
10.1101/2023.03.18.533293
Open publication

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Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory lossDOI 10.1101/2023.03.18.533293
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