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Altered T-cell reactivity in the early stages of Alzheimer's disease

30 Apr 2025

Abstract excerpt

The adaptive immune system and neurodegenerative Alzheimer's disease (AD) are intertwined in multiple ways. Recent studies have reported alterations of the adaptive immune system in early AD stages, such as preclinical AD and mild cognitive impairment (MCI) due to AD. However, the identity of specific antigenic targets and whether the respective response is beneficial or detrimental during disease progression are...

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PMID: 40320887
DOI: 10.1093/brain/awaf167

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