Article

Genomic analysis of a synthetic reversed sequence reveals default chromatin states in yeast and mammalian cells

2022-06-22

Abstract excerpt

Up to 93% of the human genome may show evidence of transcription, yet annotated transcripts account for less than 5%. It is unclear what makes up this major discrepancy, and to what extent the excess transcription has a definable biological function, or is just a pervasive byproduct of non-specific RNA polymerase binding and transcription initiation. Understanding the default state of the genome would be informati...

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Identifiers and source

Literature Corpus work: 1744c3a0-f52f-57aa-bb2c-ef53bf6117a6
DOI: 10.1101/2022.06.22.496726

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