Article

Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

2019-04-13

Abstract excerpt

<h4>Background</h4> Myeloid differentiation gives rise to a plethora of immune cells in the human body. This differentiation leaves strong signatures in the epigenome through each differentiated state of genetically identical cells. The leukemic HL-60/S4 promyelocytic cell can be easily differentiated from its undifferentiated promyelocyte state into neutrophil-and macrophage-like cell states, making it an excell...

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Literature Corpus work: 171f2ad1-d732-5ac4-9d34-663931ad2bbc
DOI: 10.1101/608695

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