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Regulation of cell cycle by the novel GATA1/TAL1/Sphingomyelin Synthase 1 ( <i>SGMS1</i> ) transcriptional axis. Implications for anti-leukemic strategies

2025-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Sphingomyelin Synthase 1 (gene name: SGMS1 ) participates in regulation of sphingolipid levels by synthesizing sphingomyelin from ceramide and phosphatidylcholine. Evidence have supported SGMS1’s functions in regulating proliferation, cell cycle, cell death and migration. While its functions have begun to be explored, very little is known about upstream regulators. Here, we demonstrate that SG...

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Literature Corpus work
112c7a4e-b034-5fcf-9f19-576390c2472b
DOI
10.1101/2025.01.19.633812
Open publication

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Regulation of cell cycle by the novel GATA1/TAL1/Sphingomyelin Synthase 1 ( <i>SGMS1</i> ) transcriptional axis. Implications for anti-leukemic strategiesDOI 10.1101/2025.01.19.633812
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