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Article

Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells.

Nucleus (Austin, Tex.) - 4 Mar 2017

Mark Welch David B, Jauch Anna, Langowski Jörg, Olins Ada L, Olins Donald E

Abstract excerpt

To understand the chromatin changes underlying differential gene expression during induced differentiation of human leukemic HL-60/S4 cells, we conducted RNA-Seq analysis on quadruplicate cultures of undifferentiated, granulocytic- and macrophage-differentiated cell forms. More than half of mapped genes exhibited altered transcript levels in the differentiated cell forms. In general, more genes showed increased...

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Identifiers

PMID: 28152343
DOI: 10.1080/19491034.2017.1285989
PMCID: PMC5403136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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