Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats

29 Mar 2012

Abstract excerpt

Methylated DNA immunoprecipitation followed by high-throughput sequencing (MeDIP-seq) has the potential to identify changes in DNA methylation important in cancer development. In order to understand the role of epigenetic modulation in the development of acute myeloid leukemia (AML) we have applied MeDIP-seq to the DNA of 12 AML patients and 4 normal bone marrows. This analysis revealed leukemia-associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Epigenetics and DNA Methylation
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22479372
DOI: 10.1371/journal.pone.0033213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of RepeatsPMID 22479372Read ↗

Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemiaSemantic proximity Read ↗

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukemiaSemantic proximity Read ↗

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid LeukemiaSemantic proximity Read ↗

Genome-wide DNA methylome analysis reveals methylation subtypes with different clinical outcomes for acute myeloid leukemia patients.Semantic proximity Read ↗

DNA methylation-based subtypes of acute myeloid leukemia with distinct prognosis and clinical featuresSemantic proximity Read ↗

Unique epigenomic signatures identify biologically significant subtypes of MDS and predict response to azacitidineSemantic proximity Read ↗

The Epigenetic Landscape of Acute Myeloid LeukemiaSemantic proximity Read ↗

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemiaSemantic proximity Read ↗

Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemiaSemantic proximity Read ↗

Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia.Semantic proximity Read ↗

DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.Semantic proximity Read ↗

Aberrant DNA Methylation in Acute Myeloid Leukemia and Its Clinical ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.