Article

Discovery of Clinically Relevant Fusions in Pediatric Cancer

2021-03-12

Abstract excerpt

<h4> A bstract </h4> <h4>Background</h4> Pediatric cancers typically have a distinct genomic landscape when compared to adult cancers and frequently carry somatic gene fusion events that alter gene expression and drive tumorigenesis. Sensitive and specific detection of gene fusions through the analysis of next-generation-based RNA sequencing (RNA-Seq) data is computationally challenging and may be confounded b...

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Literature Corpus work: 9536b3e0-883a-5999-be55-fbeb6aa4cc66
DOI: 10.1101/2021.03.11.435013

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