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Article

The landscape of long noncoding RNA-involved and tumor-specific fusions across various cancers

3 Nov 2020

Abstract excerpt

The majority of the human genome encodes long noncoding RNA (lncRNA) genes, critical regulators of various cellular processes, which largely outnumber protein-coding genes. However, lncRNA-involved fusions have not been surveyed and characterized yet. Here, we present a systematic study of the lncRNA fusion landscape across cancer types and identify >30 000 high-confidence tumor-specific lncRNA fusions (using...

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PMID: 33275145
DOI: 10.1093/nar/gkaa1119

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