Article

annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions

2019-11-12

Abstract excerpt

<h4>Background</h4> Gene fusion events are a significant source of somatic variation across adult and pediatric cancers and are some of the most clinically-effective therapeutic targets, yet low consensus of RNA-Seq fusion prediction algorithms makes therapeutic prioritization difficult. In addition, events such as polymerase read-throughs, mis-mapping due to gene homology, and fusions occurring in healthy normal...

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Literature Corpus work: 41455519-4795-53b6-b747-7e349c491282
DOI: 10.1101/839738

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