Article

IL2 enhances ex-vivo expanded regulatory T cell persistence after adoptive transfer

2019-10-15

Abstract excerpt

<h4>ABSTRACT</h4> As regulatory T cell (Treg) adoptive therapy continues to develop clinically, there is a need to determine which immunomodulatory agents pair most compatibly with Tregs to enable persistence and stabilize suppressor function. Prior work has shown that mechanistic target of rapamycin (mTOR) inhibition can increase stability of thymic Tregs. In this study we investigated the transcriptomic signatu...

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Literature Corpus work: 165b78c6-380a-5935-ac56-6f7e4b59e702
DOI: 10.1101/805531

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