Article

IL-7 improves the fitness of regulatory T cells for adoptive transfer

2023-05-18

Abstract excerpt

Adoptive regulatory T cell (Treg) trasfer represents a potential therapeutic option to control immune responses in organ transplantation, graft vs host disease, and autoimmunity, including type 1 diabetes. Treg for adoptive therapy are traditionally sorted and expanded in vitro with high doses of IL-2, showing stability and suppressive capacity, but with some limitations in terms of long-term survival once infuse...

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Literature Corpus work: 32501178-21bf-5a08-8e1a-8d218ed7c8e6
DOI: 10.22541/au.168442541.16550445/v1

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