Article

Augmented expansion of Treg cells from healthy and autoimmune subjects via adult progenitor cell co-culture

2020-12-03

Abstract excerpt

Recent clinical experience has demonstrated that adoptive regulatory T cell therapy is a safe and feasible strategy to suppress immunopathology via induction of host tolerance to allo- and autoantigens. However, clinical trials continue to be compromised due to an inability to manufacture a sufficient Treg cell dose. Multipotent adult progenitor cells (MAPC Ⓡ ) promote regulatory T cell differentiation in vitro...

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Literature Corpus work: ce73b7d2-ed6a-589d-9a01-b5f442ad27c4
DOI: 10.1101/2020.12.03.410316

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