Article

PGC-1α coordinates with Bcl-2 to control cell cycle in U251 cells through reducing ROS

2017-02-24

Abstract excerpt

B-cell lymphoma 2 ( Bcl-2 ) has a dual function, acting both as an oncogene and an anti-tumor gene. It is well known that Bcl-2 exerts its tumor promoting function through the mitochondrial pathway. However, the mechanism by which Bcl-2 suppresses tumor formation is not well understood. We have previously shown that Bcl-2 inhibits cell cycle progression from the G 0 /G 1 to the S phase after serum starvation, a...

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Literature Corpus work: 164fcd68-8d8c-52e2-b77e-e01b1f4c115d
DOI: 10.1101/111567

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