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Article

Bcl2 retards G1/S cell cycle transition by regulating intracellular ROS.

Blood - 1 Nov 2003

Deng Xingming, Gao Fengqin, May W Stratford

Abstract excerpt

Bcl2's antiapoptotic function is regulated by phosphorylation. Bcl2 also regulates cell cycle progression, but the molecular mechanism is unclear. Bcl2 is functionally expressed in mitochondria where it can act as an antioxidant that may regulate intracellular reactive oxygen species (ROS). Since ROS have been reported to act as second messengers in cell signaling, we tested whether Bcl2 phosphorylation regulates...

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Identifiers

PMID: 12855558
DOI: 10.1182/blood-2003-04-1027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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